论文部分内容阅读
目的探讨多潘立酮联合奥美拉唑治疗慢性浅表性胃炎的临床效果。方法选择2014年2月—2016年1月在景德镇市第六人民医院治疗的慢性浅表性胃炎患者88例,将患者随机分为对照组和观察组,各44例。对照组采用奥美拉唑治疗,观察组采用多潘立酮联合奥美拉唑治疗,两组患者均连续治疗3周。比较两组患者症状积分、临床效果、不良反应发生情况和复发率。结果治疗前两组症状积分比较,差异无统计学意义(P>0.05);治疗后观察组症状积分低于对照组,差异有统计学意义(P<0.05)。观察组总有效率高于对照组,差异有统计学意义(P<0.05)。观察组复发率高于对照组,差异有统计学意义(P<0.05)。两组患者治疗过程中均无严重不良反应发生。结论慢性浅表性胃炎采用多潘立酮与奥美拉唑联合治疗的临床效果显著,治疗安全性高。
Objective To investigate the clinical effect of domperidone combined with omeprazole in the treatment of chronic superficial gastritis. Methods Eighty-eight chronic superficial gastritis patients were treated in the Sixth People’s Hospital of Jingdezhen from February 2014 to January 2016. The patients were randomly divided into control group and observation group, with 44 cases in each group. The control group was treated with omeprazole, the observation group treated with domperidone combined with omeprazole, two groups of patients were treated for 3 weeks. The symptom score, clinical effect, incidence of adverse reactions and relapse rate were compared between the two groups. Results There was no significant difference in symptom scores between the two groups before treatment (P> 0.05). After treatment, symptom score of the observation group was lower than that of the control group (P <0.05). The total effective rate of observation group was higher than that of control group, the difference was statistically significant (P <0.05). The recurrence rate of the observation group was higher than that of the control group, the difference was statistically significant (P <0.05). No serious adverse reactions occurred in both groups during the course of treatment. Conclusion Chronic superficial gastritis with domperidone combined with omeprazole clinical effect is significant, safe treatment.