作者联合使用维丙胺及吡多辛治疗高脂蛋白血症42例,取得一定疗效,现报告如下。资料及方法 42例高脂蛋白血症(大多数是ⅡbⅣ型)均为本院内科病人,男20例,女22例;年龄43～60岁,平均53.4岁。并首先排除可能由于粘液性水肿、肾病综合征、糖尿病、肝胆疾患及药物(利尿剂、β受体阻滞剂、激素)等所产生的继发性高脂蛋白血症。在应用本组降脂药物前及治疗一月后各复查一次血脂。胆固醇系采用硫磷铁法,正常值为3.85～6.4,mmol/L(150～250mg/dl),甘油三酯系采用正庚烷法,正常值为0.58～1.69mmol/L(50～150mg/dl)。为了观察本组药物的确切疗效,在治疗期间不要求患者改变原来的饮食习惯。维丙胺80mg,每日一次,肌注;吡多辛10mg,一 The authors combined the use of propamidine and pyridoxine in the treatment of 42 cases of hyperlipoproteinemia, achieved a certain effect, are as follows. Materials and Methods 42 cases of hyperlipoproteinemia (mostly Ⅱ b Ⅳ type) are hospital medical patients, 20 males and 22 females; aged 43 to 60 years, mean 53.4 years old. And first rule out secondary hyperlipoproteinemia that may be due to myxedema, nephrotic syndrome, diabetes, hepatobiliary disorders and drugs (diuretics, beta blockers, hormones) and the like. In the application of lipid-lowering drugs in this group before treatment and January after each review of blood lipids. Cholesterol system using ferricyanide method, the normal value of 3.85 ~ 6.4, mmol / L (150 ~ 250mg / dl), triglycerides using n-heptane method, the normal value of 0.58 ~ 1.69mmol / L (50 ~ 150mg / dl). In order to observe the exact effect of this group of drugs, patients are not required to change their eating habits during treatment. Dimethylamine 80mg, once daily, intramuscular injection; pyridoxine 10mg, one