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为进一步研究胃幽门螺杆菌（ＨＰ）与胃炎发病的关系，对河南省食管癌和胃癌高发区１９４例１５岁～２６岁的青少年进行了胃粘膜活检和营养素生化测定。发现胃炎的组织学检出率高达９３．８％。银染色法检查ＨＰ的感染率为８５．６％，血清学法检测ＨＰ的感染率为５０．６％。活动性胃炎ＨＰ感染率为１００％，非活动性胃炎ＨＰ感染率为６５．１％。ＨＰ感染者慢性萎缩性胃炎发病优势比（Ｏｄｄｓｒａｔｉｏ）为５．５。胃癌家族史、吸烟、高盐饮食也与萎缩性胃炎发病呈正相关。结果表明：ＨＰ感染、高盐饮食和维生素缺乏可能是青少年中胃炎的发病因素。
In order to further study the relationship between Helicobacter pylori (HP) and the pathogenesis of gastritis, gastric mucosal biopsy and biochemical assays were performed on 194 adolescents aged 15 to 26 years old in esophageal cancer and high incidence area of gastric cancer in Henan province. Histological detection of gastritis found 93.8%. The infection rate of HP was 85.6% by silver staining and 50.6% by serological method. Active gastritis HP infection rate was 100%, non-active gastritis HP infection rate was 65.1%. The prevalence odds ratio of chronic atrophic gastritis in HP infected persons was 5.5. Family history of gastric cancer, smoking, high-salt diet was also positively correlated with the incidence of atrophic gastritis. The results showed that: HP infection, high-salt diet and vitamin deficiency may be the incidence of gastritis in adolescents.