糖尿病性周围神经病变(DN)是糖尿病常见的慢性并发症,我科试用灯盏花素治疗,收到满意效果,报告如下。 1 临床资料 选择符合WHO诊断标准的2型糖尿病合并周围神经病变患者88例,有典型的周围神经病变表现,如疼痛、麻木、灼热、针刺感。患者按入院次序随机分为治疗组和对照组。治疗组44例,其中男性21例,女性23例.年龄39～72岁,病程4～15年;对照组44例中男24例,女20例,年龄37～69岁,病程3.5～14年。 2 方法 病人入院后接受饮食和胰岛素治疗的同时,治疗组应用灯盏花素20ml加入生理盐水250ml静脉点滴;对照组应用维生素B_(12)500μg肌肉注射,均每日1次,共4周。观察治疗前后临床症状、全 Diabetic peripheral neuropathy (DN) is a common chronic complication of diabetes mellitus, the trial of breviscapine treatment, received satisfactory results, the report is as follows. 1 clinical data in line with the WHO diagnostic criteria for type 2 diabetes patients with peripheral neuropathy in 88 patients with typical peripheral neuropathy, such as pain, numbness, burning, acupuncture. Patients were randomly divided into treatment group and control group according to admission order. The treatment group of 44 patients, including 21 males and 23 females, aged 39 to 72 years, duration of 4 to 15 years; 44 cases of control group, 24 males and 20 females, aged 37 to 69 years, duration of 3.5 to 14 years . 2 Methods Patients admitted to the hospital after receiving diet and insulin treatment, while the treatment group with breviscapine 20ml added saline 250ml intravenous drip; the control group with vitamin B_ (12) 500μg intramuscular injection, were once daily for 4 weeks. Observed before and after treatment of clinical symptoms, all