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目的研究不良围产期胎婴儿尸检的发病情况,探讨不良围产期胎婴儿相关因素。方法回顾性分析我院2000年1月-2010年1月围产期胎婴儿尸检资料和临床资料。结果 54 462例围产儿中515进行尸检,228例胎婴儿检出先天性畸形,尸检畸形检出率为4.19‰,神经系统畸形发病率最高(58/228),其次为多个脏器混合畸形(39/228)、颌面五官系统畸形(35/228)、心血管系统畸形(24/228)、骨骼关节发育畸形(21/228)。胎儿先天性畸形活胎引产尸解178例,宫内死胎引产尸解299例,死产儿尸解2例,新生儿死亡尸解36例,围产期胎婴儿引产主要为胎儿先天性畸形及宫内死胎,新生儿死亡主要为胎儿先天性畸形、感染和缺氧,宫内死胎部份死因不明。结论尸检能确定大部分不良围产期胎婴儿的原因,能进一步证实、澄清及矫正诊断。
Objective To study the incidence of autopsy in infants with unhealthy perinatal period and to explore the related factors of infants with unhealthy perinatal period. Methods A retrospective analysis of our hospital from January 2000 -2010 January perinatal fetus autopsy data and clinical data. Results One hundred and seventy-five (4646) perinatal children underwent autopsy, and 228 fetuses with congenital anomalies were detected. The detection rate of autopsy was 4.19 ‰, and the highest incidence of neurological malformations was 58/228. The second was multiple organ deformities (39/228), maxillofacial system deformity (35/228), cardiovascular system deformity (24/228) and skeletal joint deformity (21/228). 178 cases of fetus congenital malformation live fetus induced abortion, 299 cases of intrauterine fetal fetus induced abortion, 2 cases of dead fetus autopsy, 36 cases of neonatal death autopsy, perinatal fetus baby fetus is mainly for congenital malformations and fetuses Necrosis, neonatal deaths are mainly congenital malformations of the fetus, infection and hypoxia, part of the cause of unexplained fetal death. Conclusions Autopsy can determine the cause of most unwanted perinatal infants and can confirm, clarify and correct the diagnosis.