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目的探讨雌三醇乳膏联合甲硝唑治疗萎缩性阴道炎的疗效。方法选取2013年南京市市级机关医院收治的62例绝经后妇女,随机分为对照组31例和观察组31例。对照组给予甲硝唑治疗,观察组给予雌三醇乳膏联合甲硝唑治疗。比较两组患者治疗后阴道健康评分、阴道炎症状评分、临床疗效、复发情况。结果治疗后观察组阴道弹性、湿润度、分泌物、健康总分高于对照组,p H值、瘙痒、性交痛、灼热感、分泌物及症状总分均低于对照组,差异有统计学意义(P<0.05)。观察组的总有效率高于对照组,复发率低于对照组,差异有统计学意义(P<0.05)。结论雌三醇乳膏联合甲硝唑治疗萎缩性阴道炎效果确切,是治疗萎缩性阴道炎的有效措施。
Objective To investigate the efficacy of estriol cream combined with metronidazole in the treatment of atrophic vaginitis. Methods Totally 62 postmenopausal women admitted to Nanjing Municipal Hospital in 2013 were randomly divided into control group (31 cases) and observation group (31 cases). The control group was treated with metronidazole, the observation group was given estriol cream combined with metronidazole treatment. Vaginal health score, vaginitis symptom score, clinical efficacy and recurrence were compared between the two groups. Results After treatment, the vaginal elasticity, moistening degree, secretion and health score in the observation group were higher than those in the control group. The total score of p H value, pruritus, painful intercourse, burning sensation, secretions and symptoms in the observation group were lower than those in the control group Significance (P <0.05). The total effective rate of the observation group was higher than that of the control group, and the recurrence rate was lower than that of the control group (P <0.05). Conclusion Estriol cream combined with metronidazole treatment of atrophic vaginitis is effective, is an effective treatment of atrophic vaginitis.