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动物模型可用于研究人类免疫缺陷症病毒(HIV)感染和艾滋病,主要有三种动物模型显示与人类HIV感染有很多共性,即猿猴免疫缺陷症病毒(SIV)、非灵长类慢病毒和非人灵长类HIV感染。灵长类和非灵长类慢病毒模型是继续研制艾滋病疫苗和治疗剂的关键。本文报道了这个研究领域的现状。
Animal models can be used to study human immunodeficiency virus (HIV) infection and AIDS. There are three main animal models that have many commonalities with human HIV infections: simian immunodeficiency virus (SIV), non-primate lentivirus and non-human Primate HIV infection. Primate and non-primate lentivirus models are key to continuing the development of AIDS vaccines and therapeutics. This article reports on the current status of this research area.