目的介绍一种混合性酸碱失衡的判断方法。方法先计算阴离子间隙的升高值△AG=(病人的AG-12)mmol/L,血清CO2的离均值△CO2=(27-病人的CO2)mmol/L,碳酸氢盐间隙=△AG-△CO2,以碳酸氢盐间隙偏离>+6mmol/L或<-6mmol/L为异常。结果本法不仅可判断二重酸碱失衡、混合性代谢性酸中毒,而且还可判断三重酸碱失衡,结果可靠。结论碳酸氢盐间隙具有较高的可靠性和实用性,计算简单、方便、实用,可作为酸碱失衡的常规判断使用。 Objective To introduce a mixed acid-base imbalance judgment method. The method begins with the calculation of the increase in anion gap ΔAG = (AG-12) mmol / L of patient, the mean of serum CO2 from ΔCO2 = (27-patient CO2) mmol / L, bicarbonate gap = △ CO2, the deviation of bicarbonate gap> +6 mmol / L or <-6 mmol / L is abnormal. Results This method can not only determine the double acid-base imbalance, mixed metabolic acidosis, but also determine the triple acid-base imbalance, the result is reliable. Conclusions The bicarbonate gap has high reliability and practicability. The calculation is simple, convenient and practical. It can be used as a routine judgment of acid-base imbalance.