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近来研究证明在腺瘤性增生(AH)中可发生小肝细胞癌(HCC),但术前难以检出。本文报告应用动脉内注入CO_2微泡增强的B超(US)检查此类病灶的作用。 回顾性研究51例手术病理证实为HCC中4例AH灶中有HCC的US,尤其是增强US资料。男3,女1,57～76岁(平均66岁),均有非增强US、CT平扫及血管造影检查。US增强方法:将3ml CO_2与8ml20％葡萄糖、0.5ml的25％白蛋白混合,经导管快速注入相应的动脉。US探头为 3.75MHz凸面式及7.5MHz线阵式。手术切除标本以10％的福尔马林液固定、切成4μm厚的切片进行检查,若见到大于周围再生结节的明确的膨胀性生长结节灶,内含门脉分支,则诊断为AH。4例AH灶中的HCC在非增强US上2例表现为弥漫性低回
Recent studies have demonstrated that small hepatocellular carcinoma (HCC) can occur in adenomatous hyperplasia (AH) but it is difficult to detect before surgery. This article reports the use of intra-arterial injection of CO 2 microbubble-enhanced ultrasound (US) to examine the role of such lesions. A retrospective study of 51 cases of surgically confirmed pathologically confirmed HCC in 4 cases of HCC in HCC, especially enhanced US data. Males 3, female 1,57-76 years old (mean 66 years old), all have non-enhanced US, CT plain scan and angiography. US-enhanced method: 3 ml of CO 2 was mixed with 8 ml of 20% glucose and 0.5 ml of 25% albumin and rapidly infused into the corresponding artery via a catheter. The US probes are 3.75MHz convex and 7.5MHz line array. Surgical resection specimens were fixed in 10% formalin and cut into 4 μm thick sections for examination. If a clear, dilated growth nodule larger than the surrounding regenerative nodules was seen with portal branches included, the diagnosis was AH. 4 cases of HCC in AH foci showed diffuse low back in 2 cases of non-enhanced US