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颅内何杰金病(ICHD)系指何杰金病(HD)侵犯颅内(IC),十分罕见。作者于1961~1981年,在2,185例HD中发现ICHD 12例(发病率0.5%),加上文献报道的30例,共42例。平均年龄33岁,男25例,女17例。按Rye分类法,LP型1例,NS型10例,MC型10例,LD型4例,未定型17例。临床分期:Ⅰ期4例,Ⅱ期10例,Ⅲ期5例,Ⅳ期7例,A组18例,B组8例,分期分组不明16例。临床表现为颅神经麻痹21例,运动神经障碍13例,头痛13例,癫痫发作10例,感觉障碍8例,木僵和昏迷5例,精神错乱5例,眩晕4例,脊髓压迫征4例,尿崩症3例,其它9例。颅内侵犯部位:皮层19例,脑膜11例,脑干、脑桥、脑垂体、小脑、眼眶和间脑各3例,
Intracranial Hodgkin’s disease (ICHD) refers to Hodgkin’s disease (HD) violations of intracranial (IC), is very rare. From 1961 to 1981, ICHD was found in 2,185 cases of HD (incidence of 0.5%), plus 30 cases reported in the literature, a total of 42 cases. The average age was 33 years old, 25 males and 17 females. According to Rye classification, there were 1 LP type, 10 NS type, 10 MC type, 4 LD type and 17 unconfined type. Clinical stage: 4 cases of stage Ⅰ, 10 cases of stage Ⅱ, 5 cases of stage Ⅲ, 7 cases of stage Ⅳ, 18 cases of group A, 8 cases of group B, 16 cases of unknown stage. Clinical manifestations of cranial nerve palsy in 21 cases, motor neurological disorders in 13 cases, headache in 13 cases, 10 cases of seizures, sensory disturbances in 8 cases, stupor and coma in 5 cases, 5 cases of delirium, vertigo in 4 cases, spinal cord compression syndrome in 4 cases , Diabetes insipidus in 3 cases, the other 9 cases. Intracranial invasion site: 19 cases of cortex, 11 cases of meninges, brain stem, pons, pituitary, cerebellum, orbit and the brain in 3 cases,