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目的探讨突发性聋与血清脂质代谢、血尿酸之间的关系。方法回顾性分析突发性聋住院患者100例的病史特点、血液学检查和影像学检查结果,检测其血清中甘油三酯、胆固醇、高密度胆固醇、低密度胆固醇、载脂蛋白AI、载脂蛋白B、血尿酸的含量。结果突发性聋组高密度胆固醇低于对照组,血尿酸值高于对照组,且差异有统计学意义(P<0.05),各年龄组之间的高密度胆固醇、尿酸值差异无统计学意义(P>0.05)。两组之间的甘油三酯、胆固醇、低密度胆固醇、载脂蛋白AI、载脂蛋白B值均差异无统计学意义。结论高密度胆固醇下降、尿酸代谢紊乱是突发性聋发生的危险因素。
Objective To investigate the relationship between sudden deafness and serum lipid metabolism and serum uric acid. Methods A retrospective analysis of 100 patients with sudden deafness inpatients history characteristics, hematology and imaging examination results, serum triglyceride, cholesterol, high-density cholesterol, low-density cholesterol, apolipoprotein AI, Protein B, blood uric acid content. Results Compared with the control group, the high-density cholesterol in the sudden deaf group was higher than that in the control group (P <0.05). There was no significant difference in the high-density cholesterol and uric acid levels among all age groups Significance (P> 0.05). There was no significant difference in triglyceride, cholesterol, low density cholesterol, apolipoprotein AI and apolipoprotein B between the two groups. Conclusions The high density of cholesterol and uric acid metabolism are the risk factors of sudden deafness.