论文部分内容阅读
目的探讨急性心肌梗死(AMI)合并阻塞性呼吸睡眠暂停综合征(OSAS)患者血浆中偶联因子6(CF6)的变化,以明确OSAS是否为AMI的独立危险因素。方法根据血清心肌坏死标记物检测及心电图演变与多导睡眠仪监测将100例研究病例分为急性心肌梗死组(36例)、急性心肌梗死合并OSAS组(28例)、OSAS组(20例);并设对照组(16例)。结果CF6值在AMI合并OSAS组为(402±133)pg/mL比AMI组(498±110)pg/mL明显增高(P<0.05)。AMI合并OSAS组中CF6水平与呼吸紊乱指数(AHI)呈正相关(r=0.531,P<0.05)。结论AMI合并OSAS患者血浆中CF6含量明显高于未合并者,OSAS为AMI的独立危险因素。
Objective To investigate the changes of plasma concentration of coupling factor 6 (CF6) in patients with acute myocardial infarction (AMI) complicated with obstructive sleep apnea syndrome (OSAS) and to determine if OSAS is an independent risk factor for AMI. Methods One hundred cases were divided into AMI group (36 cases), OSAS group (28 cases), OSAS group (20 cases) and AMI group according to the detection of serum myocardial necrosis markers and ECG evolution and polysomnography. ; And control group (16 cases). Results The CF6 value of OSAS group (402 ± 133) pg / mL was significantly higher than that of AMI group (498 ± 110) pg / mL group (P <0.05). There was a positive correlation between CF6 level and respiratory distress index (AHI) in OSI group (r = 0.531, P <0.05). Conclusion The plasma levels of CF6 in AMI patients with OSAS were significantly higher than those without AMI. OSAS was an independent risk factor for AMI.