用多普勒超声心动图和随机双盲法对比了卡托普利(C)和吲哒帕胺(Ⅰ)治疗50例高血压病患者5月前后的LA、IVST、PWT、LVDd、LVMI、IRT、Ei、Ai及Ai/Ei。结果两组病人血压均显著降低,IRT显著缩短。C组IVST、PWT和LVMI显著减少(P均<0.001),Ei显著增高,Ai/Ei和LA显著降低;Ⅰ组则不然。提示C能使高血压病人左室的肥厚显著消退,并显著改善左室舒张功能。 Doppler echocardiography and randomized double-blind comparison of captopril (C) and indapamide (I) treatment of 50 cases of hypertensive patients before and after 5 months of LA, IVST, PWT, LVDd, LVMI, IRT, Ei, Ai and Ai / Ei. Results The blood pressure of both groups was significantly reduced, IRT was significantly shortened. The IVST, PWT and LVMI were significantly decreased in group C (all P <0.001), Ei was significantly higher, Ai / Ei and LA were significantly decreased, but not in group Ⅰ. Tip C can hypertensive patients with left ventricular hypertrophy significantly subsided, and significantly improve left ventricular diastolic function.