在胚胎器官形成过程中 ,成纤维细胞生长因子 (FGFs)是担负上皮 间质相互作用的重要调控因子 ,特别是FGF10 ,无论在外胚层上皮还是在内皮层上皮都是重要的间质调控因子。FGFs信号对早期胚胎、四肢、牙齿、肺 支气管、肝脏和胰腺、眼睑和皮肤、颅骨、下颌腺、中枢神经系统、骨骼肌、乳腺、外生殖器、泌尿器、骨骼、晶状体等形态发生起重要调控作用 Fibroblast growth factor (FGFs) are important regulators of epithelial-mesenchymal interactions during embryonic organogenesis. FGF10, in particular, is an important interstitial regulatory factor in both epithelial and ectodermal epithelia. FGFs play an important role in the morphogenesis of early embryos, limbs, teeth, lung bronchus, liver and pancreas, eyelids and skin, skull, mandibular gland, central nervous system, skeletal muscle, mammary gland, external genitalia, urinary system, bone, lens and so on