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处于生长期的肿瘤可能释放出肿瘤相关抗原,致使血清中或在其他体液中形成免疫复合物。因此,测定循环中的免疫复合物有助干恶性疾病的诊断和估计预后。本文研究:用一种改良的 C_1q 补体结合试验,测定结肠直肠癌患者外科治疗前后的免疫复合物水平,对看作是恶性前期的良性结肠息肉患者也进行这种检查。目的在于分析循环免疫复合物与这些肿瘤的关系。静脉血标本取自100名已确诊为结肠直肠癌的患者。在外科治疗前及外科治疗后6周,3个月和随后每隔3个月分别取样。另一组血标本取自52名已洽
Tumors that are in the growth phase may release tumor-associated antigens, resulting in the formation of immune complexes in the serum or in other body fluids. Therefore, the determination of circulating immune complexes can aid in the diagnosis and prognosis of malignant diseases. This study investigated the use of a modified C_1q complement binding assay to determine the level of immune complexes before and after surgical treatment in patients with colorectal cancer. This was also performed in patients with benign colon polyps who were considered to be premalignant. The goal is to analyze the relationship between circulating immune complexes and these tumors. Venous blood samples were taken from 100 patients who had been diagnosed with colorectal cancer. Samples were taken before surgery and 6 weeks, 3 months after surgery and every 3 months thereafter. Another group of blood samples taken from 52 have been in contact