论文部分内容阅读
目的:探讨心脏磁共振中钆延迟强化程度与慢性心力衰竭患者预后的关系。方法:收集2015年1月至2016年12月,就诊于首都医科大学附属北京安贞医院慢性心力衰竭患者,行心脏磁共振检查,记录钆延迟强化是否出现,钆延迟强化程度的相关变量:钆延迟强化的异常心肌容量占总的心肌容量的百分比。同时记录两组患者的基线资料、血生化指标及冠状动脉造影术情况,通过电话及门诊对患者进行定期随访,记录主要不良心血管事件,包括心源性死亡、心脏移植。结果:经过2年的随访,其中12例患者发生心源性死亡,2例患者发生心脏移植。钆延迟强化的出现在事件组与非事件组中并无明显差异。单因素及多因素Cox回归分析发现,钆延迟强化程度可能是慢性心力衰竭患者预后的独立预测因子(OR=1.049,95%CI:1.019~1.079,P<0.001)。结论:钆延迟强化程度可能是慢性心力衰竭患者预后的独立预测因子。
Objective: To investigate the relationship between the delayed enhancement of gadolinium in heart magnetic resonance and the prognosis of patients with chronic heart failure. Methods: From January 2015 to December 2016, patients undergoing chronic heart failure were enrolled in the Beijing Anzhen Hospital, Capital Medical University. Cardiac magnetic resonance imaging (MRI) was performed. Gadolinium delayed-release enhancement was recorded. Gd Delayed enhancement of abnormal myocardial capacity as a percentage of total myocardial capacity. Baseline data, blood biochemical parameters and coronary angiography were also recorded for both groups. Regular follow-up of patients by phone and outpatient visits was recorded for major adverse cardiovascular events including cardiac death and heart transplantation. Results: After 2 years of follow-up, 12 patients developed cardiac death and 2 patients underwent heart transplantation. The appearance of delayed Gd enhancement was not significantly different between the event group and the non-event group. Univariate and multivariate Cox regression analysis showed that delayed Gd enhancement may be an independent predictor of prognosis in patients with chronic heart failure (OR = 1.049, 95% CI: 1.019-1.079, P <0.001). CONCLUSIONS: Gd-delayed potentiation may be an independent predictor of prognosis in patients with chronic heart failure.