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一般认为黄体期缺损(LPD)是黄体产生孕酮不足的结果,而雌激素分泌并无影响。不少学者持有异议:黄体中期雌二醇水平与下个周期的卵泡发育密切相关,雌二醇比孕酮更能影响早孕的预后;在月经生理中,雌二醇可为颗粒细胞增生创造良好的环境,使促卵泡激素(FSH)及促黄体生成素(LH)能作用于相应的受体上,诱导芳香化活力,合成卵泡液中之成份,最后使LH释放,作用于黄体中之LH受体,这些都是正常黄体功能所必需的,一定量的黄体中期雌二醇(750pg/ml)及孕酮(8.0ng/ml)又是怀孕及维持早孕所不可缺少的,因此,排卵前的雌二醇水平与黄体功能及孕酮
Luteal phase defect (LPD) is generally believed to be the result of corpus luteum deficiency and progesterone secretion, while estrogen secretion has no effect. Many scholars hold the objection: the mid-luteal estradiol level is closely related to follicular development in the next cycle. Estradiol is more likely to affect the prognosis of early pregnancy than progesterone. In menstrual physiology, estradiol may create granulocyte proliferation Good environment, so that follicle stimulating hormone (FSH) and luteinizing hormone (LH) can act on the corresponding receptor, inducing aroma activity, follicular fluid synthesis of the composition, and finally release of LH, the role of the corpus luteum LH receptors, all of which are necessary for proper luteal function, a certain amount of mid-luteal estradiol (750 pg / ml) and progesterone (8.0 ng / ml) are indispensable for pregnancy and early pregnancy, and therefore ovulation Pre-estradiol levels correlated with luteal function and progesterone