与发病较晚的患儿相比,早发型1型糖尿病患儿成年后发展为肾功能衰竭的可能性更小。对12032例儿童期发病的1型糖尿病患者进行研究,观察因糖尿病引起的肾功能衰竭的累积发生率。最长随访27年,结果,在4414名糖尿病病程超过15年的患者中,有33名(0.7%)发展为糖尿病相关性终末期肾病( Children with early-onset type 1 diabetes are less likely to develop renal failure later in life than children with later onset. A total of 12032 patients with childhood onset type 1 diabetes were studied and the cumulative incidence of renal failure due to diabetes mellitus was observed. With a maximum follow-up of 27 years, 33 (0.7%) of 4414 patients with diabetes over 15 years progressed to diabetic-related end-stage renal disease