充血性心力衰竭(CHF)是由于心脏器质性或功能性疾病损害心室充盈和射血能力而引起的一组临床综合征,是各种心脏病的严重阶段和最终结局。慢性充血性心力衰竭合并室性心律失常,是临床常见的急危重病症,常使病情恶化,预后不良,病死率明显增加。许多抗心律失常药因其负性肌力作用,在用于此类患者时受到限制。 Congestive heart failure (CHF) is a group of clinical syndromes caused by impaired ventricular filling and ejection ability due to organic or functional heart disease and is a serious stage and final outcome of a variety of heart diseases. Chronic congestive heart failure with ventricular arrhythmia, is a common clinical critical illness, often make the disease worse, the prognosis is poor, the mortality rate increased significantly. Many antiarrhythmic drugs are limited in their use for such patients due to their negative inotropic effect.