近年来对高嗜酸性粒细胞综合征(HES)的研究已取得不少进展.这些研究的重点主要集中在嗜酸性粒细胞(Eos)内成分的毒性、HES发生机理和病理改变、临床表现方面.综述如下.一、Eos及其与HES的关系Eos的生成很可能受单一基因控制,Eos存骨髓内的形成还受T淋巴细胞制约.个别家族易发生Eos明显增多的病种.Eos的特征性颗粒内有一电子致密的核和电子可穿透的基质,外有膜包绕.核由 In recent years, great progress has been made in the study of hypereosinophilic syndrome (HES), which mainly focuses on the toxicity of components in eosinophils (Eos), the pathogenesis and pathological changes of HES, clinical manifestations The following is a summary of Eos and its relationship with HES Eos generation is likely to be controlled by a single gene, Eos deposit in the formation of bone marrow is also restricted by T lymphocytes.Ehre family prone to Eos significantly increased diseases.Eos features Sexual particles have an electron-dense nucleus and an electron-permeable matrix surrounded by a membrane.