金属硫蛋白(metallothionein,MT)在体内参与锌的代谢。它不仅能结合锌,而且膳食锌在转录水平上也调节MT的表达;另外多种激素对MT合成的诱导又可使锌从血浆转移至肝脏.MT可提供锌到金属酶中及DNA结合的锌指区,也可作为清道夫来保护细胞和锌的供体用作稳定细胞膜。本文主要阐明(rh)IL-1α、rhIL-6、细胞外锌和地塞 Metallothionein (MT) is involved in the metabolism of zinc in the body. It not only binds to zinc but also mediates the expression of MT at the transcriptional level as well as the induction of MT synthesis by various hormones which in turn transfers zinc from the plasma to the liver.MT provides zinc to metalloenzymes and DNA binding The zinc finger region, also serves as a scavenger to protect the cells and the donor of zinc serves as a stable cell membrane. This article mainly elucidates (rh) IL-1α, rhIL-6, extracellular zinc and dexamethasone