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从理论上探讨认为钙通道阻滞剂,可有抗惊厥作用且在体内外的癫痫发作模型中得到证实。镇静剂氟苯桂嗪(flunafizne)应用于人类,业已取得成效。常用的异搏定与硫氮(艹卓)酮钙拮抗剂,已发现可抑制卡马西平在体内生物转化与产生毒性。本文试验性研究评定硝苯吡啶(双氢吡啶衍化物)抗癫痫的效果。12例顽固性癫痫患者,(女性4例,男性8例,年龄20～58岁,平均患病时间为2～42年)。10例为复合型部分性癫痫伴继发全身性癫痫,一例仅有部
In theory, it is considered that calcium channel blockers can have anticonvulsant effects and are confirmed in the model of seizures in vitro and in vivo. Sedation agent flubenzuril (flunafizne) used in humans, has achieved results. Commonly used verapamil and sulfur nitrogen (acenaphthene) calcium antagonist, has been found to inhibit carbamazepine in vivo biotransformation and toxicity. This experimental study evaluated the effect of nifedipine (dihydropyridine derivative) antiepileptic. 12 patients with intractable epilepsy, (4 females, 8 males, aged 20 to 58 years, the average duration of illness is 2 to 42 years). 10 cases of complex partial epilepsy with secondary generalized epilepsy, only one case of the Ministry