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Iq7611始载于神农本草经,本草纲目等书记载:药性甘平无毒,具破血软坚,活血解毒等功能,有治疗崩中带下、痛疽恶疮等效用。民间用以治疗癌症。自1973年以来,我们对Iq7611进行了植物学、植物化学和抗癌等药理研究。1979年开始对Iq7611进行了比较系统的放射增敏实验研究,结果显示,对体外培养的Hela细胞,对小鼠MA737乳腺癌以及对裸鼠移植性人肠粘液腺癌均有显著的放射增敏作用,尤其对乏氧肿瘤细胞的放射增敏作用更为显著,说明Iq7611是一种乏氧细胞增敏剂。药理实验还证明Iq7611口服毒性很低,并有增强免疫功能和保护造血细胞的作用等特点。
Iq7611 was originally published in the Shennongboshi Classics. The Compendium of Materia Medica and other books recorded that the medicinal Ganping is non-toxic, it has the functions of blood stasis, blood circulation, detoxification, and other functions. The folk used to treat cancer. Since 1973, we have conducted phytochemical, phytochemical and anti-cancer pharmacological studies on Iq7611. A systematic radiosensitization study of Iq7611 was conducted in 1979. The results showed that there was significant radiosensitization to HeLa cells cultured in vitro, to MA737 breast cancer in mice, and to transplantable intestinal mucinous adenocarcinoma in nude mice. The role, especially for radiosensitization of hypoxic tumor cells is more significant, indicating that Iq7611 is a hypoxic cell sensitizer. Pharmacological experiments also proved that oral toxicity of Iq7611 is very low, and it has the characteristics of enhancing immune function and protecting hematopoietic cells.