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客观评估板层角膜移植术 (Lamellarkeratoplasty ,LKP)治疗基质型活动期单纯疱疹性角膜炎 (herpessimplexkeratitis ,HSK)的临床价值。方法 :对 71例 ( 71只眼 )HSK基质型活动期患者分两组 ,一组 ( 33例 )行LKP ,另一组 ( 38例 )行穿透性角膜移植术 (pene tratingkeratoplasty ,PKP) ,比较两组病人术后的疗效与并发症。结果 :LKP组术后在视力、角膜移植片排斥反应发生率、原发病复发率与内眼手术并发症发生率等方面均明显优于PKP组 (P <0 0 1)。结论 :在适应症范围内 ,成功的LKP具有清除病灶彻底、排斥反应发生率低、无内眼手术并发症等优点 ,是治疗基质型活动期HSK的理想方法。
Objective To evaluate the clinical value of lamellar keratoplasty (LKP) in the treatment of herpes simplex keratitis (HSK). Methods: 71 patients (71 eyes) were divided into two groups. One group (33 cases) underwent LKP, the other group (38 cases) underwent pene tratingkeratoplasty (PKP) The curative effect and complication of the two groups were compared. Results: The postoperative LKP group was significantly better than the PKP group in visual acuity, the incidence of rejection of primary corneal graft, the incidence of primary recurrent disease and the incidence of intraocular surgery complications (P <0.01). CONCLUSIONS: Successful LKP has the advantages of clear lesions, low incidence of rejection, and no complication of endoscopic surgery in the field of indications. It is an ideal method for treating HSK in patients with active matrix.