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尼莫地平配合仙台合剂（甘露醇、地塞米松、维生素Ｅ）治疗急性脑梗塞病人。治疗组及对照组（单纯尼莫地平）各４０例，治疗第１１、１４、２１、２８天神经机能改善程度治疗组均优于对照组，以２～３周更明显（Ｐ＜０００１）。经颅多普勒显示两组治疗后大脑中动脉血流速度均较治疗前显著减慢（Ｐ＜０００１）。仙台合剂可使再灌流导致的ＭＤＡ增加及ＳＯＤ活力下降发生逆转（Ｐ＜０００１），认为二者合用既可纠正缺血脑组织的低灌流状态，又可使缺血的脑组织免遭自由基的继发性破坏，值得推广使用。
Nimodipine with Sendai mixture (mannitol, dexamethasone, vitamin E) in patients with acute cerebral infarction. Treatment group and control group (nimodipine alone) 40 cases, the treatment of the 11th, 14th, 21st and 28th days to improve the degree of neural function in the treatment group were better than the control group, 2 to 3 weeks was more significant (P <0 001 ). Transcranial Doppler showed that the blood flow velocity of middle cerebral artery in both groups was significantly lower than that before treatment (P <0001). Sendai Mixture could increase MDA and decrease SOD activity induced by reperfusion (P <0001), which suggested that the combination of both could correct the hypoperfusion state of ischemic brain tissue and protect the ischemic brain from Secondary destruction of free radicals, it is worth promoting the use of.