论文部分内容阅读
目的 分析 Askin 瘤临床病理特征,为该肿瘤的诊断与治疗提供依据。方法 对6 例 Askin 瘤组织常规处理, H E、 P A S、网状纤维染色。结果 临床上为青少年胸肺部肿块伴疼痛,生存期短,预后差,2 年生存率33 % ,5 年生存率为0 。组织学上以稀少的纤维血管间质将小圆、卵圆瘤细胞围绕成巢状或小叶状结构。网染细胞间网状纤维少或无, P A S染色部分病例( + ) 。结论 Askin 瘤为一种位于胸肺部神经内分泌源性的高度恶性肿瘤,临床病理与胸壁外尤文瘤、原始神经外胚瘤比较无显著性意义。
Objective To analyze the clinicopathological features of Askin tumor and provide evidence for its diagnosis and treatment. Methods Six cases of Askin tumors were treated routinely with H E, P A S, and reticular fibers. Results Clinically adolescent chest and lung masses were associated with pain, short survival, and poor prognosis. The 2-year survival rate was 33% and the 5-year survival rate was 0. Histologically, the small round, oculoma cells are surrounded by sparse fibrovascular interstitium in a nested or lobular structure. There were few or no reticulocytes between the reticulocytes, and P A S stained some cases (+). Conclusion Askin tumor is a kind of high malignant tumor located in the neuroendocrine of thoracic lung. There is no significant difference between clinical pathology and extrathoracic Ewing tumor and primitive neuroectodermal tumor.