脑桥中央髓鞘溶解症(CPM)是一种罕见的脱髓鞘疾病,以往仅见于尸检病理诊断,常被认为是致死性疾病。随着诊断技术的进步,尤其是CT、MRI的广泛应用,CPM的生前诊断已成为可能,对CPM的病因及发病机制、流行病学、临床表现、影像学及其辅助检查、治疗有了进一步的认识。1病因和发病 Central pontine myelinolysis (CPM) is a rare demyelinating disease, previously only seen in autopsy pathological diagnosis, often considered a lethal disease. With the advancement of diagnostic techniques, especially CT and MRI, the prenatal diagnosis of CPM has become possible. The etiology and pathogenesis of CPM, epidemiology, clinical manifestations, imaging and its auxiliary examination and treatment have been further improved Understanding. 1 etiology and pathogenesis