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目的观察应用三联疗法治疗幽门螺杆菌阳性消化性溃疡的临床效果。方法选取医院收治的消化性溃疡患者98例,按照患者就诊ID号奇、偶数分为观察组和对照组,每组49例。对照组仅接受奥美拉唑治疗,观察组接受三联疗法治疗。观察比较2组患者治疗有效率及生活质量评分改善情况。结果所有患者均顺利完成治疗,观察组总有效率为95.92%,高于对照组的75.51%(P<0.05);治疗后,2组各项生活质量评分较治疗前均降低,且观察组各项生活质量评分均优于对照组(P<0.05)。结论应用三联疗法治疗幽门螺杆菌阳性消化性溃疡疗效显著,可有效根治幽门螺杆菌感染及消化性溃疡,提高患者术后生活质量。
Objective To observe the clinical effect of triple therapy on Helicobacter pylori-positive peptic ulcer. Methods A total of 98 patients with peptic ulcer admitted to the hospital were enrolled in this study. They were divided into observation group and control group according to the patient’s ID number and even number. Each group included 49 cases. The control group received only omeprazole, and the observation group received triple therapy. Observation and comparison of two groups of patients with treatment efficiency and quality of life scores improve. Results All patients were successfully treated. The total effective rate in the observation group was 95.92%, which was higher than that in the control group (75.51%, P <0.05). After treatment, the quality of life scores of the two groups were lower than those before treatment, Quality of life items were better than the control group (P <0.05). Conclusion The triple therapy is effective in treating H.pylori-positive peptic ulcer and can effectively cure Helicobacter pylori infection and peptic ulcer and improve postoperative quality of life.