在遗传咨询门诊中,对135例有产前诊断指征的孕妇进行了羊水细胞培养及 AFP 测定,发现18三体综合征及 Kilnefelter 综合征各一例,并经引产后病理解剖及胎心血培养证实。据目前发表的资料,国外也属罕见,国内尚无此类病例报导。18三体综合征系多发性先天畸形,智力发育障碍,Klinefelter 氏综合征系先 In the genetic counseling clinic, 135 pregnant women with prenatal diagnosis indications of amniotic fluid cell culture and AFP determination and found that 18 cases of trisomy syndrome and Kilnefelter syndrome in each case, and post-partum pathological anatomy and fetal heart blood culture Confirmed. According to the current published information, foreign countries are also rare, no such cases reported in China. Trichotillomania syndrome 18 Department of multiple congenital malformations, mental retardation, Klinefelter’s syndrome Department first