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目的:主要讨论了不同手术入路方式治疗第三脑室颅咽管瘤的临床效果。方法:选取我院于2014年8月-2015年4月间收治的51例第三脑室颅咽管瘤患者,随机将其分为观察组、对照组。其中观察组患者26例,接受经皮质-侧脑室入路手术治疗;对照组患者25例,接受经胼胝体-透明隔-穹窿间入路手术治疗,比较两组患者治疗效果。结果:在本次研究中,观察组患者的肿瘤全部切除比例为88.46%(23/26),对照组患者肿瘤全部切除的比例为60.0%(15/25),两组结果相比,差异具有统计学意义(P<0.05)。比较两组患者的手术时间、住院时间、术中出血量等数据,观察组明显优于对照组(P<0.05)。结论:经皮质-侧脑室入路的手术治疗方式在治疗第三脑室颅咽管瘤中发挥着重要作用,具有安全性高、疗效显著等优点,应该在临床上做进一步推广。
Objective: To discuss the clinical effect of different surgical approachs on the treatment of craniopharyngioma in the third ventricle. Methods: Fifty-one patients with craniopharyngioma in 51 cases admitted to our hospital from August 2014 to April 2015 were randomly divided into observation group and control group. Among them, 26 patients in the observation group were treated by transcortical-lateral ventricle surgery; 25 patients in the control group were treated by trans-corpus-translumenal-fornix approach and the therapeutic effect was compared between the two groups. Results: In this study, the total resection rate was 88.46% (23/26) in the observation group and 60.0% (15/25) in the control group, the differences between the two groups were statistically significant Statistical significance (P <0.05). The data of operation time, hospitalization time, intraoperative blood loss and so on were compared between the two groups. The observation group was significantly better than the control group (P <0.05). Conclusion: Surgical treatment of transcortical - lateral ventricle approach plays an important role in the treatment of craniopharyngioma in the third ventricle. It has the advantages of high safety and significant curative effect. It should be further popularized clinically.