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流行病学调查表明,心脑血管疾病目前已成为危害人类健康的主要疾病,噻氯匹啶片(ticlopidine,Tic)引入中国后经过几年的临床应用,在防治血管栓塞性疾病上取得了明显效果,该药物是一类新型的抗血小板凝集药物,具有高效、安全等优点。1 Tic的作用机制1.1对血小板(Plt)的作用Tic可抑制Plt的活性,并抑制Plt的粘附、聚集和释放反应。机制如下:①对二磷酸腺苷(ADP)的效应。离
Epidemiological studies have shown that cardiovascular and cerebrovascular diseases have become the major diseases endangering human health. After several years of clinical application of ticlopidine (Tic) tablets in China, significant progress has been made in the prevention and treatment of vascular embolism Effect, the drug is a new type of anti-platelet aggregation drugs, with high efficiency, safety and other advantages. 1 Tic mechanism of action 1.1 The role of platelet (Plt) Tic can inhibit the activity of Plt, and inhibit Plt adhesion, aggregation and release reactions. The mechanism is as follows: ① the effect of adenosine diphosphate (ADP). from