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目的观察降纤酶治疗急性脑梗死的疗效、血液纤溶功能变化和治疗时间窗。方法选 32例急性脑梗死患者予以降纤酶治疗。另选 30例急性脑梗死患者予以 70 6代血浆加葛根素作对照组。结果 2周末治疗组显效率 6 0 % ,极高于对照组 17% ( P<0 .0 1)。纤溶功能检查 :除发病 49小时~ 1周内用药者 PAI无变化外 ,余均有显著或极显著差异 ( P<0 .0 5或 P<0 .0 1)。结论降纤酶治疗脑梗死的疗效极显著高于对照组 ,并提高纤溶活性。
Objective To observe the curative effect of defibrase on acute cerebral infarction, changes of blood fibrinolytic function and treatment time window. Methods Thirty-two patients with acute cerebral infarction were treated with defibrase. Another 30 patients with acute cerebral infarction were given 70 6 generations of plasma plus puerarin for the control group. Results Two weeks after treatment, the effective rate was 60% in the treatment group, which was significantly higher than that in the control group (17%, P <0.01). Fibrinolytic function test: In addition to the onset of 49 hours to 1 week, there was no change in patients with PAI, Yu were significantly or very significant differences (P <0. 05 or P <0. Conclusion The therapeutic effect of defibrase on cerebral infarction is significantly higher than that of the control group, and fibrinolytic activity is improved.