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对门脉高压病人具有特征性的十二指肠病变鲜有报道。本研究旨在了解对门脉高压病人十二指肠糜烂的内镜所见组织学特征及临床背景。 方法:1983年1月~2001年8月间440例经内镜下硬化疗法(EVS)和/或曲张静脉套扎(EVL)治疗的门脉高压病人;同期450例慢性肝炎病人;450例因体检作上消化道内镜检查者为对照组。对部分病人行超声内镜对十二指肠壁进行观察。用靛氰绿试验(ICG)测定肝脏血流及肝脏功能。 结果:门脉高压症病人中68例15.5%。有十二指肠糜烂。慢性肝炎中有4例(占0.9%),而对照组有2例(占0.4%),门脉高压组十二指肠糜烂的发生率显著高于其他两组。十二指肠糜烂程度的分级为:轻度指斑点或红色斑纹或
There are few reports of characteristic duodenal lesions in patients with portal hypertension. The purpose of this study was to understand the endoscopic histological features and clinical background of duodenal erosions in patients with portal hypertension. Methods: From January 1983 to August 2001, 440 patients with portal hypertension undergoing endoscopic sclerotherapy (EVS) and / or varicose vein ligation (EVL) were enrolled; 450 patients with chronic hepatitis and 450 patients Physical examination for upper gastrointestinal endoscopy for the control group. Some patients underwent endoscopic ultrasound to observe the duodenal wall. Liver blood flow and liver function were measured with indocyanine green test (ICG). Results: 68 cases of portal hypertension patients 15.5%. Have duodenal erosion. There were 4 cases of chronic hepatitis (0.9%), while the control group had 2 cases (0.4%). The incidence of duodenal erosions in portal hypertension group was significantly higher than the other two groups. The degree of duodenal erosion is graded as: slight or spotted or red markings