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目的分析我院重症监护室(ICU)多重耐药菌分布和耐药情况。方法采用回顾性调查方法,对我院2013~2015年多重耐药菌目标监测数据进行分析。结果 1.所检出多重耐药菌中以革兰阴性杆菌为主。革兰阴性杆菌占87.04%,其中大肠埃希菌占8.33%,肺炎克雷伯菌占24.54%,鲍曼不动杆菌占38.89%,铜绿假单胞菌占7.87%;革兰阳性球菌占12.96%,其中表皮葡萄球菌占3.24%,金黄色葡萄球菌占8.80%;2.多重耐药革兰阴性杆菌的耐药率中总体对庆大霉素、左氧氟沙星、头孢他定耐药程度比较严重,对头孢哌酮舒巴坦、亚胺培南已有耐药情况,多重耐药革兰阳性球菌的耐药率中总体对替加环素、万古霉素、利奈唑胺比较敏感;3.多重耐药菌标本中93.06%都来源于痰液。结论多重耐药菌同样是结核重症监护病区患者感染的重要病菌,应加强对高危科室和易感人群的监控,遏制多重耐药菌的感染和传播。
Objective To analyze the distribution and drug resistance of multidrug-resistant bacteria in intensive care unit (ICU) in our hospital. Methods The retrospective survey method was used to analyze the surveillance data of multiple drug-resistant bacteria from 2013 to 2015 in our hospital. Results 1. Gram-negative bacilli were found mainly in multi-drug-resistant strains. Gram-negative bacilli accounted for 87.04%, of which Escherichia coli accounted for 8.33%, Klebsiella pneumoniae accounted for 24.54%, Acinetobacter baumannii accounted for 38.89%, Pseudomonas aeruginosa accounted for 7.87%; Gram-positive cocci accounted for 12.96 %, Of which Staphylococcus epidermidis accounted for 3.24% and Staphylococcus aureus accounted for 8.80% .2. The drug resistance rates of multidrug-resistant Gram-negative bacilli were generally severe to gentamicin, levofloxacin and ceftazidime, Resistant to cefoperazone sulbactam and imipenem have been resistant to multi-drug resistant Gram-positive cocci in general resistance to tigecycline, vancomycin, linezolid; 3. Multiple 93.06% of drug-resistant bacterial species were all from sputum. Conclusions Multidrug-resistant bacteria are also important pathogens in patients with tuberculosis intensive care ward. The surveillance of high-risk departments and susceptible populations should be strengthened to prevent the infection and spread of multi-resistant bacteria.