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作者报告1984年至1989年间105例何杰金病(HD)中18例人类免疫缺陷病毒(HIV)相关性HD患者的临床和病理资料,并回顾文献记载的HIV相关性HD。18例HIV相关性HD中,同性恋者14例。静脉滥用药物者3例,两者兼有之1例。中位年龄33岁(24～47岁)。17例为混合细胞型(MC)HD,1例为结节硬化型(NS)HD。除1例外均为晚期疾病(Ⅲ-Ⅳ)。部分患者起初对化疗有效.但最终将复发。13例死于复发性HD。可供评价的患者中位生存期为14个月。105例HD按年龄分为两组:一组为15～3d岁和大于50岁(HD典型发病年龄组)。另一组为35～49岁。8/18例HIV相关性HD在35—49岁年龄组中
The authors report the clinical and pathological data of 18 cases of human immunodeficiency virus (HIV)-associated HD in 105 cases of Hodgkin’s disease (HD) from 1984 to 1989, and reviewed the documented HIV-related HD. Of the 18 HIV-related HD cases, 14 were homosexual. There were 3 cases of intravenous drug abuse and 1 case of both. The median age is 33 years (24-47 years old). 17 cases were mixed cell type (MC) HD and 1 case was tuberous sclerosis (NS) HD. All but one exception were advanced disease (III-IV). Some patients initially responded to chemotherapy but eventually relapsed. Thirteen patients died of recurrent HD. The median survival for patients who can be evaluated is 14 months. 105 cases of HD were divided into two groups by age: one group was 15 to 3 years old and more than 50 years old (HD typical age group). The other group is 35 to 49 years old. 8/18 HIV-related HDs in the 35-49 age group