利用昆明种小白鼠为供试动物,发现甲酚紫、齐通红、若丹明B在小鼠肿瘤组织和正常组织内的荧光特征(包括荧光光谱的形状及随时间的变化规律)有明显区别,可望用于肿瘤的荧光诊断。 三种染料的蒸馏水溶液,按5-10mg/kg,通过尾静脉对小鼠注射。注药后的不同时刻,对肿瘤组织和对照进行荧光检测。 Using Kunming species of mice as test animals, it was found that the fluorescence characteristics of cresyl violet, Qitonghong, and Rhodamine B in mouse tumor tissues and normal tissues (including the shape of fluorescent spectra and their variation with time) are significantly different. , It is expected to be used for the fluorescence diagnosis of tumors. Aqueous solutions of the three dyes were injected at a dose of 5-10 mg/kg through the tail vein. At different times after the injection, tumor tissues and controls were subjected to fluorescence detection.