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本工作采用玻璃微电极记录兔离休十二指肠平滑肌细胞内电变化,并同步记录兔离休平滑肌条的收缩,从而分析慢波,前电位和动作电位与肌收缩的关系。结果表明:(1)慢波能引起兔十二指肠近端平滑肌收缩,并呈1:1的关系;(2)在慢波引起肌收缩的基础上,前电位可使肌收缩进一步加强;(3)兔十二指肠近端的平滑肌自发放电产生的动作电位,其幅度为52.1±8.5mv(n=30),在形式上有的呈单一放电,有的呈簇状放电,前者放电频率为1~4次/秒,后者为6次/秒;(4)三种电活动引起肌条收缩的幅度以动作电位最大,前电位次之,慢波最小。上述资料表明,兴奋性高的兔十二指肠近端的平滑肌细胞内不同的电活动可引起不同的收缩。
In this work, the glass microelectrode was used to record the electrical changes of retired duodenal smooth muscle cells of rabbits and the contraction of smooth muscle strips of retired rabbits was recorded simultaneously. The relationship between the slow wave, anterior potential and action potential and muscle contraction was analyzed. The results show that: (1) Slow wave can induce the proximal duodenal smooth muscle contraction, and showed a 1: 1 relationship; (2) the slow wave induced muscle contraction on the basis of the potential before the muscle contraction can be further strengthened; (3) The action potentials produced by spontaneous discharge of rabbit proximal duodenum smooth muscle were 52.1 ± 8.5mv (n = 30), some were single discharge in the form and some were cluster discharge , The former discharge frequency of 1 to 4 times / sec, which is 6 times / sec; (4) three kinds of electrical activity caused by muscle contraction amplitude to the maximum action potential, the potential before the second, slow wave minimum. The above data show that the excitability of rabbit proximal duodenal smooth muscle cells in different electrical activities can cause different contraction.