硝基吡啶为一种钙离子拮抗药,具有强有力的血管舒张作用,尤其对治疗心绞痛、慢性心衰以及高血压效果较好曾报告副作用少。然而,最近有两篇报告:服用本品后出现肺水肿和严重低血压,从而引起人们的注意。作者最近也观察到二例病人服硝苯吡啶后几个小时出现脑缺血。病例一:一位72岁男性患者,因突然发生右侧偏瘫、伴失语而住院。十年前诊断有缺血性心脏病 Nitropyridine is a calcium antagonist with potent vasodilator effects, especially for the treatment of angina pectoris, chronic heart failure and high blood pressure. However, there have been two recent reports of pulmonary edema and severe hypotension after taking this product, which attracted people’s attention. The authors also recently observed cerebral ischemia in a few hours after taking nifedipine in two patients. Case 1: A 72-year-old male patient was hospitalized for sudden onset of right hemiplegia with aphasia. Ten years ago diagnosed with ischemic heart disease