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奥卡西平是卡马西平的10-酮基衍生物,具有独特的药动学特征。临床已应用于局限性和强直-阵挛性癫痫、三叉神经痛及情感性精神障碍的治疗。奥卡西平比卡马西平具有更好的耐受性,故能有效地取代卡马西平用于那些不耐受卡马西平的患者及同其它药物有配伍禁忌的患者的治疗。
Oxcarbazepine is a 10-keto derivative of carbamazepine with unique pharmacokinetic properties. Clinical has been applied to limitations and tonic - clonic epilepsy, trigeminal neuralgia and emotional disorders. Oxcarbazepine is more tolerant than carbamazepine and can effectively replace carbamazepine in patients who are intolerant of carbamazepine and in patients with incompatibility with other drugs.