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目的 初步评价FDGSPECT/CT符合线路同机图像融合在肿瘤诊断及复发监测中的应用价值 .方法 经临床确诊的恶性肿瘤及恶性肿瘤治疗后怀疑复发或残留的患者 5 3例 (治疗前诊断 8例、治疗后疑复发 45例 ) .经SPECT/CT同机联合扫描行FDG显像检查 ,用二次迭代法加衰减校正进行影像重建 ,与同期CT或 (和 )MR检查相比较 .结果 在治疗前诊断组中 ,8例恶性肿瘤患者FDG显像均呈阳性 ,CT(MR)亦全部发现病灶 ,但不能对病灶进行有效定性 ;在治疗 (手术、放疗、化疗 )后疑复发的 45例患者中FDG与CT(MR)的假阳性、假阴性、真阳性、真阴性分别为0 ,4,3 2 ,9和 3 ,7,2 9,6;FDG灵敏度、特异性、阳性预测值、阴性预测值分别为 8·89%、10 0 %、10 0 %、69 2 % ;而CT或 (和 )MR分别为 80 6%、66 7%、90 6%、46 2 % .同机融合由CT提供的详细解剖资料能准确定位恶性病灶 .结论 带有X线CT的符合线路的SPECT/CT同机融合FDG显像是一种新的有效的核医学显像方法 ,尤其是对治疗后残余或复发的肿瘤 ,较CT(MR)及其它功能性检查图像等更具有较特异的定性和准确性定位诊断价值 ,值得临床推广应用
OBJECTIVE: To evaluate the value of FDGSPECT / CT coincidence-line image fusion in oncology diagnosis and recurrence monitoring.Methods Fifty-three patients with suspected or recurrent malignant tumors after malignant tumor were diagnosed , Suspected to relapse after treatment of 45 cases) .Fluid imaging by FDG imaging combined with SPECT / CT scan, with two iterative method plus attenuation correction imaging reconstruction, compared with the same period of CT or (and) MR examination.Results In the treatment FDG imaging was positive in 8 cases of malignant tumors in the pre-diagnosis group. CT (MR) also found all the lesions, but not in the lesions. 45 patients suspected of relapse after surgery (radiotherapy and chemotherapy) The false positive, false negative, true positive and true negative of FDG and CT (MR) were 0, 4, 32, 9 and 3, 7, 2, 9 and 6, respectively; FDG sensitivity, specificity, positive predictive value and negative The predicted values were 8 · 89%, 100%, 100%, 69 2% respectively, while CT or MR was 80 6%, 66 7%, 90 6% and 46 2% respectively. Detailed anatomical data provided by CT can accurately locate the malignant lesions.Conclusion The line-conforming SPECT / CT fusion with FDG imaging is a new and effective nuclear imaging method, especially for residual or recurrent tumors after treatment, more specific and qualitative than CT (MR) and other functional examination images The diagnostic value of the accuracy of positioning, it is worth clinical application