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放射治疗舌癌46例,其中男31例,女15例,年龄30～78岁。病理分类为鳞癌43例,未分化癌1例,肉瘤1例,囊性腺样上皮癌1例。舌前部癌36例,舌根癌10例。采用单纯放疗41例,舌动脉插管化疗+放疗1例,放疗+全身化疗4例。5年生存率41.3%。放疗+全身化疗有3例生存5年以上。6例放疗后复发二程放疗,5例未行化疗,皆于1年内死亡,1例骨转移二程放疗辅以化疗8年仍健在。放疗合并化疗可能会提高Ⅲ,Ⅳ期病人的5年生存率。作者建议对Ⅲ,Ⅳ期舌癌采用放存+化疗的综合性治疗。
Radiotherapy for 46 cases of tongue cancer, including 31 males and 15 females, aged 30 to 78 years old. Pathological classification included 43 cases of squamous cell carcinoma, 1 case of undifferentiated carcinoma, 1 case of sarcoma, and 1 case of cystic adenoid epithelial carcinoma. There were 36 cases of tongue anterior cancer and 10 cases of tongue base cancer. 41 cases were treated with radiotherapy alone, 1 case was treated with tongue arterial chemotherapy plus radiotherapy, and 4 cases were treated with radiotherapy + systemic chemotherapy. The 5-year survival rate is 41.3%. Radiotherapy + systemic chemotherapy in 3 cases survived more than 5 years. Six cases of recurrence and second course radiotherapy after radiotherapy, 5 cases did not undergo chemotherapy, all died within 1 year, 1 case of bone metastases and 2 cycles of radiotherapy supplemented with chemotherapy were still alive for 8 years. Radiotherapy combined with chemotherapy may increase the 5-year survival rate of patients with stage III and IV. The authors propose a comprehensive treatment of tongue cancer in stage III and IV using radix plus chemotherapy.