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生物被膜状态的霍乱弧菌具有极强的环境适应性和超高的感染性,生物被膜的发育调控研究对霍乱弧菌的宿主感染和环境适应非常重要。本文综述了近年来霍乱弧菌生物被膜研究结果,包括霍乱弧菌生物被膜的组成、发育和环境调控,尤其着重阐述了各种环境因子对霍乱弧菌生物被膜发育的影响,包括细菌自体信号分子、自然环境因子和宿主信号分子。
Biofilm Vibrio cholerae has strong environmental adaptability and high infectivity. The developmental regulation of biofilm is very important for Vibrio cholerae host infection and environmental adaptation. This review summarizes the results of biofilm research on Vibrio cholerae in recent years, including the composition, development and environmental regulation of Vibrio cholerae biofilms, with particular emphasis on the effects of various environmental factors on the development of Vibrio cholerae biofilm, including bacterial autosomal signaling molecules , Natural environmental factors and host signaling molecules.