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[目的]探讨大肠癌的组织学分型、浸润与淋巴结转移的关系。[方法]回顾性研究725例大肠癌根治标本中具有淋巴结转移的275例病理资料。[结果]未分化癌最常发生淋巴结转移(3/4) ,其它依次为鳞癌(2/3)、印戒细胞癌(7/12)、低分化腺癌(56/92)、粘液腺癌(56/100)、中分化腺癌(135/381)及高分化腺癌(16/131)。其中肠管全层浸润210例 ,侵犯深肌层57例 ,浅肌层8例。[结论]大肠癌的淋巴结转移与组织学分型、肿瘤细胞的分化程度及浸润的范围具有密切关系。
[Objective] To investigate the relationship between histological type, infiltration and lymph node metastasis in colorectal cancer. [Method] A total of 275 pathological specimens with lymph node metastasis in 725 specimens of colorectal cancer were retrospectively studied. [Results] The most common occurrence of undifferentiated carcinoma was lymph node metastasis (3/4), followed by squamous cell carcinoma (2/3), signet ring cell carcinoma (7/12), poorly differentiated adenocarcinoma (56/92), mucinous gland Cancer (56/100), moderately differentiated adenocarcinoma (135/381), and well-differentiated adenocarcinoma (16/131). Including 210 cases of full-thickness intestine infiltration, invasion of deep muscle in 57 cases, shallow muscle in 8 cases. [Conclusion] The lymph node metastasis of colorectal cancer is closely related to the histological type, the degree of tumor cell differentiation and the extent of infiltration.