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目的:调查传染性非典型肺炎(severeacuterespiratorysyndrome,SARS)患者中合并有慢性病者的临床流行病学特点。方法:回顾性分析680例SARS患者中合并慢性病的种类、数目和患者的年龄、主要临床症状和体征。结果:有合并症的SARS患者平均年龄远高于无并发症者(t=12.6,P<0.05),具有1种以上并发症的病例数为87例,占12.8%,最多者1例有4种并发症。糖尿病、高血压是最常见的SARS患者并发症,分别为20和19例,检出率分别是2.9%和2.8%;合并慢性病者出现呼吸困难、腹痛症状的概率显著高于无合并慢性病者(χ2=11.955,8.265,P<0.05)。有慢性病患者的收缩压犤(16.0±2.4)mmHg,1mmHg=0.133kPa犦和舒张压犤(9.3±1.6)mmHg犦均显著高于无基础疾患者犤(15.3±1.1),(8.9±1.6)mmHg犦(t=5.054,3.120,P<0.05)。结论:①SARS患者最常见的并发症是糖尿病和高血压。②有并发症者多为老年SARS患者,有并发症者常预后不良。③有并发症的SARS患者呼吸功能更易受损,出现呼吸困难。
Objective: To investigate the clinical epidemiological characteristics of patients with chronic diseases in patients with severe acute respiratory syndrome (SARS). Methods: A retrospective analysis of 680 cases of SARS patients with chronic diseases, the number of patients and their age, the main clinical symptoms and signs. Results: The average age of SARS patients with complications was much higher than those without complications (t = 12.6, P <0.05). The number of cases with more than one kind of complications was 87 (12.8%) and the most one was 4 Complications. Diabetes and hypertension were the most common complication of SARS patients in 20 and 19 cases respectively, the detection rates were 2.9% and 2.8% respectively. The incidence of dyspnea and abdominal pain in patients with chronic diseases was significantly higher than those without chronic complications χ2 = 11.955, 8.265, P <0.05). Systolic blood pressure (16.0 ± 2.4) mmHg, 1 mmHg = 0.133 kPa 舒 and diastolic blood pressure 犤 (9.3 ± 1.6) mmHg 慢 in patients with chronic diseases were significantly higher than those in patients without underlying diseases (15.3 ± 1.1, 8.9 ± 1.6, mmHg 犦 (t = 5.054,3.120, P <0.05). Conclusion: ① The most common complications of SARS patients are diabetes and hypertension. ② complications are mostly elderly patients with SARS, complications are often poor prognosis. ③ SARS patients with complications of respiratory function more vulnerable to breathing difficulties.