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患者男,农民,22岁,因牙痛于1993年10月17日来我院就诊.口服甲硝唑(河南省医药工业公司新星制药厂生产,批号920617)0.4g,tid;红霉素0.25g,qid.3d后,忽感头痛、头晕,突然摔倒.意识丧失,双眼上翻,呼吸急促,牙关紧闭,口吐白味,四肢抽搐,持续约2min.5min后,神志渐清,但仍有头晕、恶心、腹痛,且伴腹泻.次日,神志清晰,神经系统检查未见异常体征,脑电图检查也无异常.10月22日,患者再服甲硝唑0.4g,tid,且停服红霉素.2d后上述表现重新出现.随后停服甲硝唑,症状又消失,至今患者未再复发.患者平素身体健康,既往无癫痫病史,也未服过甲硝唑,这次服用甲硝唑后引起癫痫样发作.停药后消失.再
Patients male, peasant, 22 years old, came to our hospital because of toothache on October 17, 1993. Oral metronidazole (Henan Pharmaceutical Industry Company Nova pharmaceutical production, batch number 920617) 0.4g, tid; erythromycin 0.25g , qid.3d, suddenly feel headache, dizziness, sudden fall. Loss of consciousness, eyes upturned, shortness of breath, teeth closed, spit vomiting, limbs twitch, continued for about 2min. There is still dizziness, nausea, abdominal pain, and with diarrhea the next day, clear consciousness, no abnormal signs of neurological examination, EEG examination was normal .On October 22nd, patients with metronidazole 0.4g, tid, And stopped taking erythromycin .2d after the above-mentioned reappearance of performance .After stopping metronidazole, the symptoms disappeared, so far no recurrence of patients .In general, patients with good health, no previous history of epilepsy, nor served metronidazole, which After taking metronidazole epileptic seizure caused. Stop and disappear