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目的了解金湾区农村孕妇亚临床甲状腺疾病的患病率,金湾区农村孕妇亚临床甲状腺疾病与不良妊娠结局的关系。方法采集孕妇周围静脉血3~4m L装于干燥试管中,留取血清标本,采用化学发光的方法检测孕妇血清中的促甲状腺素(TSH)、游离三碘甲状腺原氨酸(FT3)、游离甲状腺素(FT4)水平。结果亚临床甲减8例,患病率为0.23%(初产妇占62.5%,经产妇占37.5%),亚临床甲亢19例,患病率为5.35%(初产妇31.5%,经产妇68.5%),不良妊娠的风险增加。大部分病例尚未结束妊娠,有待继续追踪妊娠及分娩过程的并发症。结论重视围产期保健工作,加强孕妇甲状腺功能筛查率,使妊娠期亚临床甲状腺疾病的早发现、早诊断、并加强患者孕期的母婴监护,尽早发现妊娠的并发症并及时治疗,改善妊娠结局,减少不良妊娠的发生率,积极查找发病原因,减低妊娠期亚临床甲状腺疾病的患病率,提高出生人口的素质,促进优生优育。
Objective To investigate the prevalence of subclinical thyroid diseases in rural pregnant women in Jinwan District and the relationship between subclinical thyroid diseases and adverse pregnancy outcomes in rural pregnant women in Jinwan District. Methods Peripheral venous blood of pregnant women was collected from 3 to 4 ml in a dry test tube. Serum samples were collected for detection of thyroid-stimulating hormone (TSH), free triiodothyronine (FT3), free Thyroxine (FT4) levels. Results Subclinical hypothyroidism in 8 cases, the prevalence was 0.23% (62.5% of primipara, maternal accounted for 37.5%), subclinical hyperthyroidism in 19 cases, the prevalence was 5.35% (primipara 31.5%, 68.5% ), The risk of adverse pregnancy increases. Most cases have not completed the pregnancy, pending the follow-up of pregnancy and childbirth complications. Conclusions Emphasis is placed on perinatal health care, the screening rate of thyroid function in pregnant women is strengthened, the early detection and early diagnosis of subclinical thyroid diseases in pregnancy are strengthened, and the maternal and child monitoring during pregnancy is strengthened. The pregnancy complications are detected as soon as possible and treated Pregnancy outcomes, reduce the incidence of adverse pregnancy, and actively find the cause of the disease, reduce the prevalence of subclinical thyroid disease during pregnancy, improve the quality of the population of birth, and promote prenatal and postnatal care.