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冬眠药物对植物神经尤其是交感神经有强力的阻滞作用,能使痉挛期的代谢降低,减少能量消耗,减轻肌肉痉挛,改善酸中毒并具有强有力的镇静催眠作用,因此人工冬眠在治疗破伤风有很高的评价.本院以人工冬眠治疗破伤风62例,兹介绍如下. 治疗方法 1.本组病例入院后均用人工冬眠治疗,其中一号冬眠者52例,四号冬眠者10例.氯丙嗪及异丙嗪每公斤体重1毫克,嘧啶每公斤2毫克,2岁以下不用嘧啶.将冬眠药物加入5%葡萄糖盐水或生理盐水500毫升内静脉滴注,开始每分钟40～50滴,以后维持速度每分钟20滴,根据病情控制速度,即当阵发性抽搐频繁、间歇时间短,或有喉痉挛时,应加速滴注,否则可给维持速度.每一次剂量结束以后可以重复应用.本组有一例每天应用5次剂量连续18日方使病人脱险.对有强烈抽搐窒息病例静脉注
Hibernation drugs on the autonomic nerve especially sympathetic strong block, can reduce the spasm of metabolism, reduce energy consumption, reduce muscle spasms, improve acidosis and have a strong role in sedation and hypnosis, artificial hibernation in the treatment of broken Cold injury has a high rating .Hospital artificial hibernation treatment of 62 cases of tetanus, are introduced as follows. Treatment 1. The patients were admitted to artificial hibernation after treatment, of which 52 cases of No. 1 sleeper, No. 4 sleeper 10 Cases of chlorpromazine and promethazine 1 mg per kilogram of body weight, pyrimidine 2 mg per kilogram, no pyrimidine under the age of 2. The hibernation drug was added to 5% glucose saline or saline 500 ml intravenous infusion began to 40 ~ 50 drops, after the maintenance of the rate of 20 drops per minute, according to the disease control speed, that is, when the paroxysmal convulsions, intermittent time is short, or laryngospasm, should be accelerated drip, or to maintain the speed of each dose after the end Can be repeated application of this group of patients with a daily dose of 5 doses of 18 consecutive days to make the patient out of danger of convulsions and asphyxia cases intravenous injection