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贫血作为慢性阻塞性肺疾病(COPD)肺外效应,影响病情和预后。COPD相关性贫血机制:长期慢性炎症使红细胞生成减少、破坏增多;可利用铁减少、红系造血祖细胞增生受损、平衡破坏、营养不良等;吸烟干扰红细胞生成引发贫血,胆茶碱抑制COPD红细胞增殖。COPD相关性贫血病因病机为本虚标实,脾肾本虚至关重要。预防和处理COPD相关性贫血具有重要的临床意义。未来期待系统、深入地研究病因病机及防治措施,强化辨证论治。
Anemia as chronic obstructive pulmonary disease (COPD) extrapulmonary effects affect the disease and prognosis. COPD-related mechanisms of anemia: Chronic inflammation of the red blood cells to reduce the generation of increased damage; availability of iron decreased erythroid hematopoietic progenitor cell proliferation, balance damage, malnutrition, etc .; smoking interference erythropoiesis-induced anemia, cholophyllin inhibition of COPD Erythrocyte proliferation. COPD-related anemia pathogenesis-based virtual real spleen and kidney vital importance. Prevention and treatment of COPD-related anemia has important clinical significance. Looking forward to the future system, in-depth study of etiology and pathogenesis and prevention and treatment measures to strengthen the syndrome differentiation.