多原发癌临床并不少见,其发生可能与病人的肿瘤易感性有关,影响肿瘤易感性的因素有饮食及环境影响;癌前病变(大肠息肉、某些慢性炎症);遗传因素及免疫功能缺陷等。本文对本院收治的2例多原发癌病人进行外周血淋巴细胞染色体及免疫功能观察。 Multiple primary cancers are not uncommon in clinical practice. Their occurrence may be related to the patient’s susceptibility to cancer. Factors that affect susceptibility to cancer include dietary and environmental effects; precancerous lesions (colon polyps, certain chronic inflammation); genetic factors and immune function Defects and so on. In this paper, the chromosome and immune function of peripheral blood lymphocytes were observed in 2 cases of multiple primary cancers treated in our hospital.