作者报告1例39岁男性结肠直肠腺癌转移患者用抗独特型抗体(α-id)免疫后的免疫反应性。患者已接受手术治疗,并在术后接受放射性治疗。术后将近两年发现肺转移,即开始用多克隆17-1A α-id羊抗体进行免疫治疗,共注射8剂α-id,每次4mg明矾沉淀的抗体,治疗期间未发现新的转移。此后对两个肺转移灶作了切除术,并再注射两次α-id。在免疫治疗前及第一次注射α-id后 The authors report the immunoreactivity of a 39-year-old male with colorectal adenocarcinoma metastases immunized with an anti-idiotypic antibody (α-id). The patient had undergone surgery and received radiotherapy after surgery. Lung metastases were found in the past two years. Immunotherapy with polyclonal 17-1A α-id sheep antibody was started. Eight doses of α-id were injected, and 4 mg of alum precipitated each time. No new metastasis was found during treatment. Thereafter, two lung metastases were resected and two more α-ids were injected. Before immunotherapy and after the first injection of α-id